Paediatric nasal polyps in cystic fibrosis

Incidence and evolution of nasal polyps in children and adolescents with cystic fibrosis.

UNLABELLED Nasal polyps are a clinical sign of alert for investigating Cystic Fibrosis (CF). AIMS To study the incidence of nasal polyps in children and adolescents with cystic fibrosis, its possible association with age, gender, clinical manifestations, genotype and sweat chlorine level, and its evolution with topical steroid therapy. METHODS Clinical symptoms, sweat chlorine level and gen...

Incidence and evolution of nasal polyps in children and adolescents with cystic fibrosis Summary

Glycohistochemical characteristics of nasal polyps from patients with and without cystic fibrosis.

OBJECTIVE To investigate whether cystic fibrosis (CF)-related nasal polyps exhibit significantly distinct glycohistochemical characteristics when compared with single vs massive nasal polyps obtained from patients without CF. DESIGN Glycohistochemical characteristics were identified by means of 8 histochemical probes, including 5 plant lectins (peanut, gorse seed, wheat germ, Maackia amurensi...

Exhaled nitric oxide in paediatric asthma and cystic fibrosis.

Nitric oxide (NO) is present in exhaled air of humans. This NO is mostly produced in the upper airways, whereas basal NO excretion in the lower airways is low. Children with Kartagener's syndrome have an almost total lack of NO in nasally derived air, whereas adult asthmatics have increased NO in orally exhaled air. NO excretion was measured in the nasal cavity and in orally exhaled air in 19 h...

Maintaining Respiratory Health in Cystic Fibrosis Patients

Cystic fibrosis (CF) is an inherited disease that primarily affects the lungs and the digestive system, however, it also affects a number of other organs and systems. More than 90% of mortality of  CF patients is due to lung complications.  Healthy lungs are important for a long life for people with CF, We will discuss two important topics for maintaining respiratory health. Chronic use of drug...